The impact of osteoarthritis development on locomotor activity and muscle inflammation and metabolism in a rodent model

What the research hopes to achieve

The aim of this study is to investigate the development of the muscle atrophy in a rodent pain model of osteoarthritis. Since inflammation is an important feature of OA pathology, and it is associated with the progression of OA pain, as well as being a major factor in driving muscle atrophy, the impact of OA on muscle inflammation and atrophy is being studied

 

Work Package	Biomarkers (WP2)
Principal Investigator	Prof Victoria Chapman (Nottingham)
Investigator	Nuria Casanova